COVID-19 associated with long-term cognitive dysfunction
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Much has been learned about SARS-CoV-2, the virus that causes the novel coronavirus, since the beginning of the COVID-19 pandemic. However, questions remain about the long-term impact of the virus on our bodies and brains. New research reported at the Alzheimer's Association International Conference® (AAIC®) 2021, held virtually and in Denver found associations between COVID-19 and persistent cognitive deficits, including the acceleration of Alzheimer's disease pathology and symptoms.
A significant hurdle in developing therapeutics and care models for Alzheimer's disease that work for people of all ethnic and racial backgrounds is the recruitment and retention of traditionally underrepresented groups in clinical trials. At the Alzheimer's Association International Conference® (AAIC®) 2021, in Denver and virtually, researchers shared new evidence-based insights into why people from communities of color do and do not choose to participate in clinical trials.
* Removal of race adjustments to equations that estimate kidney function would increase the number of people categorized as having chronic kidney disease. * There are several modifications for removing race that vary in their expected impact on predicted kidney function values and associated clinical decisions. * Among race-free equations, the one based on blood measurements of cystatin C would likely result in the smallest changes.
A just-published study coins a new metric: the "mortality cost of carbon." That is, how many future lives will be lost--or saved--depending on whether we increase or decrease our current carbon emissions. If the numbers hold up, they are quite high.
Transgender and gender nonbinary adults in the U.S. are more likely to report worsening memory and thinking, functional limitations and depression compared to cisgender (non-transgender) adults, according to two studies reported at the Alzheimer's Association International Conference® (AAIC®) 2021 in Denver and virtually.
A new study shows that people who eat a diet that includes at least half a serving per day of foods high in flavonoids like strawberries, oranges, peppers and apples may have a 20% lower risk of cognitive decline. The research is published in the July 28, 2021, online issue of Neurology, the medical journal of the American Academy of Neurology. The study looked at several types of flavonoids, and found that flavones and anthocyanins may have the most protective effect.
People with larger waistlines, high blood pressure and other risk factors that make up metabolic syndrome may be at higher risk for having a second stroke and even dying than people who do not have metabolic syndrome, according to a meta-analysis published in the July 28, 2021, online issue of Neurology, the medical journal of the American Academy of Neurology.
People with type 2 diabetes diagnosed during youth have a high risk of developing complications at early ages and have a greater chance of multiple complications within 15 years after diagnosis. The findings are the culmination of a first-of-its-kind trial funded largely by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), part of the National Institutes of Health.
Tragically, the opioid epidemic has led to an increase in accidental and premature deaths, which has also increased the number of hearts available for potential organ donation. Receiving a heart from a donor who used illicit drugs does not impact the recipient's survival, according to a group of researchers from Virginia, Arizona and Indiana.
Johns Hopkins Medicine researchers say they have added to evidence that the compound farnesol, found naturally in herbs, and berries and other fruits, prevents and reverses brain damage linked to Parkinson's disease in mouse studies.