Exosome formulation developed to deliver antibodies for choroidal neovascularization therapy
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Researchers from the Institute of Process Engineering (IPE) of the Chinese Academy of Sciences, Beijing Chaoyang Hospital and the University of Queensland have developed a new formulation based on regulatory T-cell exosomes (rEXS) to deliver vascular endothelial growth factor (VEGF) antibodies for choroidal neovascularization therapy.
Researchers at Texas A&M University are pushing organ-on-a-chip devices to new levels that could change the way clinicians approach cancer treatment, particularly ovarian cancer. A team has recently submitted a patent disclosure with the Texas A&M Engineering Experiment Station.
A phenomenon known from quantum systems could now make its way into biology: In a new study published in Physical Review X, researchers from the Max Planck Institute for Dynamics and Self-Organization (MPI-DS) in Goettingen show that the notion of topological protection can also apply to biochemical networks. The model which the scientists developed makes the topological toolbox, typically used only to describe quantum systems, now also available to biology.
Duke University scientists have developed tests sensitive enough to detect and measure microscopic particles of coal ash in soil, even at concentrations so low and sizes so small that other tests would likely miss them. The four new tests complement tests previously developed at Duke to detect coal ash contamination in water and larger particles of coal ash in soil.
A new study, led by University of Minnesota Twin Cities engineering researchers, shows that the stiffness of protein fibers in tissues, like collagen, are a key component in controlling the movement of cells. The groundbreaking discovery provides the first proof of a theory from the early 1980s and could have a major impact on fields that study cell movement from regenerative medicine to cancer research.
Hydrogels developed at Rice University mimic intestines when lined with epithelial cells. A study by Rice and Baylor College of Medicine proved hydrogels in various stiffnesses are valuable for learning the dynamics of pathogens that cause diarrhea and other intestinal diseases.
The touchscreen technology used in billions of smartphones and tablets could also be used as a powerful sensor, without the need for any modifications.
An innovative testing platform that more closely mimics what cancer encounters in the body may allow for more precise, personalized therapies by enabling the rapid study of multiple therapeutic combinations against tumor cells. The platform, which uses a three-dimensional environment to more closely mirror a tumor microenvironment, is demonstrated in research published in Communications Biology.
Researchers from the School of Biomedical Engineering & Imaging Sciences at King's College London have automated brain MRI image labelling, needed to teach machine learning image recognition models, by deriving important labels from radiology reports and accurately assigning them to the corresponding MRI examinations. Now, more than 100,00 MRI examinations can be labelled in less than half an hour.
Researchers from Nanyang Technological University, Singapore (NTU Singapore), in collaboration with French specialty materials leader Arkema, have developed a tougher, safer bicycle helmet using a combination of materials. The new helmet prototype has higher energy absorption, reducing the amount of energy transferred to a cyclist's head in the event of an accident and lowering the chances of serious injury.