Addressing diversity in Alzheimer's clinical trials
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A significant hurdle in developing therapeutics and care models for Alzheimer's disease that work for people of all ethnic and racial backgrounds is the recruitment and retention of traditionally underrepresented groups in clinical trials. At the Alzheimer's Association International Conference® (AAIC®) 2021, in Denver and virtually, researchers shared new evidence-based insights into why people from communities of color do and do not choose to participate in clinical trials.
Transgender and gender nonbinary adults in the U.S. are more likely to report worsening memory and thinking, functional limitations and depression compared to cisgender (non-transgender) adults, according to two studies reported at the Alzheimer's Association International Conference® (AAIC®) 2021 in Denver and virtually.
Johns Hopkins Medicine researchers say they have added to evidence that the compound farnesol, found naturally in herbs, and berries and other fruits, prevents and reverses brain damage linked to Parkinson's disease in mouse studies.
Formal volunteering in later life is beneficial for both physical and psychological well-being. However, research has shown that older adults with key advantages, such as wealth, are more likely to volunteer and reap its benefits. In a new study appearing in the American Journal of Preventive Medicine, published by Elsevier, investigators found that lower-wealth volunteers may experience even greater health gains than higher-wealth volunteers.
Lonely, older adults are nearly twice as likely to use opioids to ease pain and two-and-a-half times more likely to use sedatives and anti-anxiety medications, putting themselves at risk for drug dependency, impaired attention, falls and other accidents, and further cognitive impairment, according to a study by researchers at UC San Francisco.
What The Study Did: Survey data were used to investigate the relationship between loneliness and high-risk medication use in adults older than age 65.
What The Study Did: The association between Medicare eligibility at age 65 and changes in racial and ethnic disparities in access to care and self-reported health was evaluated in this study.
In a report published by Personality and Social Psychology Bulletin, University of Illinois Chicago researchers detail findings from three studies that explore the connection between political ideology, attitudes, and beliefs toward diversity.
Researchers at Washington State University have recently identified a DNA region known as VNTR2-1 that appears to drive the activity of the telomerase gene, which has been shown to prevent aging in certain types of cells. Knowing how the telomerase gene is regulated and activated and why it is only active in certain cell types could someday be the key to understanding how humans age and how to stop the spread of cancer.
What The Study Did: Using survey responses from students in some Pittsburgh, Pennsylvania, high schools, researchers investigated how experiences of bullying based on race/ethnicity/national origin and other marginalized identities are associated with outcomes for health, mental health and violence among adolescents.