Johns Hopkins Medicine researchers say they have added to evidence that the compound farnesol, found naturally in herbs, and berries and other fruits, prevents and reverses brain damage linked to Parkinson's disease in mouse studies.
After gaining world attention by 'unboiling' egg protein, Flinders University scientists have now used an Australian-made novel thin film microfluidic device to manipulate Beta-lactoglobulin (β-lactoglobulin), the major whey protein in cow's, sheep's and other mammals. In the latest application, published in Molecules, College of Science and Engineering experts have combined the capabilities of the VFD with a new form of biosensor called TPE-MI, which is an aggregation-induced emission luminogen (AIEgen).
Over the last few decades, neurodegenerative diseases became one of the top 10 global causes of death. Researchers worldwide are making a strong effort to understand neurodegenerative diseases pathogenesis, which is essential to develop efficient treatments against these incurable diseases. A team of researchers found out the implication of lysosomes in the spread of Parkinson's disease.
The use of digital health technologies across health care and drug development has accelerated. A new paper titled "Digital Progression Biomarkers as Novel Endpoints in Clinical Trials: A Multistakeholder Perspective," co-authored by experts across diverse disciplines, highlights how new remote monitoring technologies present a tremendous opportunity to advance digital medicine in health care even further, specifically in Parkinson's disease.
Well over six million people globally have been diagnosed with Parkinson's disease (PD), which has an enormous impact on the lives of patients, their families, and caregivers and is incurring mounting costs for society.
Scientists synthesized chemical compounds that can stop the degeneration of neurons in Alzheimer's, Parkinson's, and other severe brain pathologies.
Researchers from Kumamoto University, Japan have found that a component derived from turmeric essential oil, ar-turmerone, and its derivatives act directly on dopaminergic neurons to exert a neuroprotective effect on tissue cultures of a Parkinson's disease model. The effect appears to be due to the enhancement of cellular antioxidant potency through Nrf2 activation. The researchers believe that the ar-turmerone derivatives identified in this study can be utilized as new therapeutic agents for Parkinson's disease.
The blood-brain barrier protects the brain and is notoriously hard to get past for drug delivery, making it difficult to treat disorders in the central nervous system. In a mice study, a team of researchers from the University of Copenhagen used a novel approach to study the barrier and in detail characterized a Trojan horse technique to help to solve the challenge.
When it comes to post-menopausal hormone therapy, the type, route and duration all play a role in reducing the risk of neurodegenerative diseases.
The major cause of Parkinson's Disease is a dysregulation of immune genes central for fighting against viruses, a new study reveals. Researchers from the University of Copenhagen show that this dysregulation leads to a malfunction in the cell's powerhouse, which cannot produce sufficient energy for neurons to stay alive, causing them to gradually die.