Cell death discovery could lead to new treatment for COPD
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Inhibiting necroptosis, a form of cell death, could yield a new treatment approach for chronic obstructive pulmonary disease (COPD), an inflammatory lung condition also known as emphysema, new research shows. The study, by a team of Australian and Belgian researchers, revealed elevated levels of necroptosis in patients with COPD. By inhibiting necroptosis activity in the lung tissue of COPD patients the researchers found a significant reduction in chronic airway inflammation and lung damage.
African American mothers continue to have the lowest breastfeeding rates, even as the breastfeeding rates have risen in the US over the past 25 years.
An alternate-day intermittent fasting schedule offered less fat-reducing benefits than a matched "traditional" diet that restricts daily energy intake, according to a new, 3-week randomized trial involving 36 participants.
Scientists today track electrical signals and voltage changes in neurons and muscle cells by labeling individual cells or probing with electrodes. UC Berkeley and Stanford scientists have developed a new type of sensor that employs a sheet of graphene to get a continuous measure of electric field in these tissues. Electric fields change graphene's reflectance. The physicists found a way to amplify and measure the changes caused by action potentials in a beating embryonic chicken heart.
Scientists at Weill Cornell Medicine have developed a computational technique that greatly increases the resolution of atomic force microscopy, a specialized type of microscope that "feels" the atoms at a surface. The method reveals atomic-level details on proteins and other biological structures under normal physiological conditions, opening a new window on cell biology, virology and other microscopic processes.
Proteins are encoded by genes - however, this information is divided into small coding sections, which are only assembled during a process called splicing. Various combinations are possible, some of which are still unknown. Dr. Robin Herbrechter and Professor Andreas Reiner from the junior research group Cellular Neurobiology at Ruhr-Universität Bochum (RUB) now systematically analysed alternative splicing in the family of ionotropic glutamate receptors (iGluRs), which is essential for signal processing in the brain.
Researchers from the Nara Institute of Science and Technology have found that plants balance growth and genome maintenance by organizing their responses to damage. Plants can't replace dead cells as animals do, and must deal with DNA damage without halting growth. Combined control of the plant hormones cytokinin and auxin allows plants to organize different DNA damage responses while minimizing cell death. This study will have broad applications to research on plants and other organisms.
A University of Iowa team has found that babies twitch during a sleep stage called quiet sleep, not just during REM sleep. The results may show there's more communication between snoozing infants' brains and motor systems than previously known. Results appear in the journal Current Biology.
The information presented in this study is primarily positioned to benefit scientists and experts in Cellular Physiology and Histochemistry where new tools to discover therapeutic targets for muscle atrophy are needed. The study outlines the development of a new fluorescent reporter mouse line to detect changes in mitophagy activity. These findings could revolutionize treatment strategies and possibly facilitate interventions to reverse disuse-induced muscle atrophy.
Does evolution explain why we can't resist a salty chip? Researchers at NC State University found that differences between the elemental composition of foods and the elemental needs of animals can explain the development of pleasing tastes like salty, umami and sweet.