DeepMind is partnering with EMBL to make the most complete and accurate database yet of the predicted human protein structures freely and openly available to the scientific community The AlphaFold Protein Structure Database will enable research that advances understanding of these building blocks of life, accelerating research across a variety of fields. AlphaFold's impact is already being realised by early partners researching neglected diseases, studying antibiotic resistance, and recycling single-use plastics.
Advances in microscopy reveal how the human genome organises itself in three-dimensional space at much higher resolution than previously possible. A new study finds that transcription generates a force that moves across DNA strands like ripples through water. The discovery may have future implications for the understanding of genetic diseases such as Cornelia de Lange syndrome, developmental disorders linked to chromatin folding, and open new avenues of research in genome fragility and cancer development.
Carnegie Mellon University researchers have identified a way to bridge two neuronal approaches traditionally used in isolation, resulting in a richer understanding of neuronal activity.
The Feinberg group's latest model mimics physiologic loads on engineering heart muscle tissues, yielding an unprecedented view of how genetics and mechanical forces contribute to heart muscle function.
A collaboration across three continents at the frontiers of physics, biology, and engineering co-led by Maurizio Porfiri at NYU Tandon, applied super computing muscle and special software to a novel simulation of the Venus' flower basket sponge.
No one wants bad breath -- not when visiting friends and family, at a job interview, and especially not on a first date. Smelly breath can make things awkward, but it also is a natural warning sign, indicating that serious dental issues are occurring. Now, researchers reporting in ACS Nano have constructed a portable, thumb-sized device that diagnoses bad breath by quickly "sniffing" exhalations for the gas that makes it stinky -- hydrogen sulfide.
During the height of the pandemic, some hospitals were overwhelmed with patients seeking treatment for COVID-19. This situation could happen again during future outbreaks, especially with SARS-CoV-2 variants of concern on the rise. Now, researchers reporting in ACS' Analytical Chemistry have developed a blood test to predict which people infected with COVID-19 are most likely to experience serious symptoms, which could help health care workers prioritize patients for hospitalization and intensive care.
An international team of researchers led by Georgia Tech is combining soft scalp electronics and virtual reality in a brain-interface system, recently published in Advanced Science.
One of the main problems preventing optimal regeneration following peripheral nerve injuries is that axons within severed nerves have difficulty regenerating and reaching their target. This may be attributed in part to misguided axons that sprout in multiple directions, decreasing probability to reach their target organs. A new technique, engineered by researchers at Bar-Ilan University in Israel, fills a nerve conduit with gel containing physical and chemical components that promote and align axon regrowth.
Researchers from the Antimicrobial Resistance (AMR) Interdisciplinary Research Group (IRG) at Singapore-MIT Alliance for Research and Technology (SMART), MIT's research enterprise in Singapore, alongside collaborators from Biobot Analytics, Nanyang Technological University (NTU) and Massachusetts Institute of Technology (MIT), have successfully developed an innovative, open-source molecular detection method that is able to detect and quantify the B.1.1.7 (Alpha) variant of SARS-CoV-2.