Nanomaterials found in consumer and health-care products can pass from the bloodstream to the brain side of a blood-brain barrier model with varying ease depending on their shape - creating potential neurological impacts that could be both positive and negative, a new study reveals.
Why are gold deposits found at all? Gold is famously unreactive, and there seems to be little reason why gold should be concentrated, rather than uniformly scattered throughout the Earth's crust. Now an international group of geochemists have discovered why gold is concentrated alongside arsenic, explaining the formation of most gold deposits
We generated a mouse model for a subgroup of schizophrenia patients by feeding Glo1 knockout mice VB6-deficent diets (KO/VB6(-)). We found that the KO/VB6(-) mice accumulated methylglyoxal (MG) in the brain and showed schizophrenia-like behavioral impairments. Furthermore, we found aberrant gene expression related to mitochondria function in the prefrontal cortex (PFC) of the KO/VB6(-) mice. Finally, we demonstrated abnormal mitochondrial respiratory function and enhanced oxidative stress in the PFC of KO/VB6(-) mice.
Bacteria found in cow stomachs can be used to digest polyesters used in textiles, packaging, and compostable bags, according to a new study by the open access publisher Frontiers. Plastic is notoriously hard to break down, but microbial communities living inside the digestive system of animals are a promising but understudied source of novel enzymes that could do the trick. The new findings present a sustainable option for reducing plastic waste and litter, co-opting the great metabolic diversity of microbes.
As smart watches are increasingly able to monitor the vital signs of health, including what's going on when we sleep, a problem has emerged: those wearable, wireless devices are often disconnected from our body overnight, being charged at the bedside.
Zeolites are extremely porous materials: Ten grams can have an internal surface area the size of a soccer field. Their cavities make them useful in catalyzing chemical reactions and thus saving energy. An international research team has now made new findings regarding the role of water molecules in these processes. One important application is the conversion of biomass into biofuel.
Welcome a new member in the family of superconducting polyhydrides: A team led by Skoltech professor Artem R. Oganov studied the structure and properties of ternary hydrides of lanthanum and yttrium and showed that alloying is an effective strategy for stabilizing otherwise unstable phases YH10 and LaH6, expected to be high-temperature superconductors.
Researchers have developed a more efficient platform for studying proteins that play a key role in regulating gene expression. The approach uses engineered yeast cells to produce enzyme and histone proteins, conduct biochemical assays internally, and then display the results.
A comparison of observed global energy technology costs, with forecasts generated by models and forecasts predicted by human experts, showed that both forecasting methods underestimated cost reductions. This suggests that decisions based on forecasts may be overestimating the cost of climate mitigation and points to the need to further improve forecasting methods.
The computer model, developed under the lead management of researchers at TU Graz, simulates the cyclical changes in the membrane potential of a cancer cell using the example of human lung adenocarcinoma and opens up completely new avenues in cancer research.