What The Study Did: Researchers report their study found no association in SARS-CoV-2 positivity rates among health care workers wearing respirator masks compared with medical masks when performing nonaerosolizing routine patient care.
All coronaviruses produce four primary structural proteins and multiple nonstructural proteins. However, the majority of antibody-based SARS-CoV-2 research has focused on the spike and nucleocapsid proteins. A study published in PLOS Biology by Anna Heffron, Irene Ong and colleagues at the University of Wisconsin-Madison, USA, suggests that immune responses may develop against other proteins produced by the SARS-CoV-2 virus.
A blood gene profile associated with a high risk of dying from a severe lung disease can also predict poor outcomes in patients with COVID-19, a multicenter retrospective study led by the University of South Florida Health (USF Health) demonstrated. The risk profile based on 50 genes could help customize how COVID-19 is treated, improve allocation of limited health care resources such as intensive care beds and ventilators, and potentially save lives.
A multidisciplinary analysis by a group of Brazilian scientists, published on-line in the journal Scientific Reports on June 21, 2021, revealed that three major factors accounted for the geographic spread of SARS-COV-2 across Brazil, as well as the massive flow of people in search of hospital care throughout the country, during the first wave of the pandemic in 2020.
What The Study Did:Â This study demonstrated a decrease in respiratory virus detections and a decline in antibiotic prescribing rates for respiratory tract infections during the COVID-19 pandemic.
What The Study Did: Using administrative healthcare data on 2.9 million households, this study suggests that events that lead to small and informal social gatherings, such as birthdays, and in particular, children's birthdays, are a potentially important source in SARS-CoV-2 transmission.
What The Study Did: Results of this study suggest race-specific disparities in SARS-CoV-2 testing and COVID-19 hospital outcomes seen in adults also exist among children, after accounting for several clinical and sociodemographic factors thought to play a role in the disease.
What The Study Did: This qualitative study reports that, in the midst of a major public health crisis, the erosion of family-centered care practices was associated with a dramatic impact on the experiences of family members of patients who died.
Researchers from NUS Yong Loo Lin School of Medicine's Infectious Diseases Translational Research Programme have discovered that the use of a common antibiotic, doxycycline, in combination with TB drug treatment, reduces the size of lung cavities and accelerates markers of lung recovery. This was done in a trial with 30 pulmonary tberculosis patients.
A comprehensive health-screening program in rural northern KwaZulu-Natal, South Africa, has found a high burden of undiagnosed or poorly controlled non-communicable diseases, according to a study published in The Lancet Global Health.