Mucus and mucins may become the medicine of the future
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The body is filled with mucus that keeps track of the bacteria. Now, researchers from the University of Copenhagen present the first method for producing artificial mucus. They hope that the artificial mucus, which consists of sugary molecules, may help to develop completely new, medical treatments.
University of California San Diego School of Medicine researchers identified a possible link between inadequate exposure to ultraviolet-B (UVB) light from the sun and an increased risk of colorectal cancer.
New research has shown myelosuppressive chemotherapy destabilises gut microbiome in patients with solid organ cancers. The study from SAHMRI and Flinders University assessed the gut health of men and women who underwent conventional chemotherapy on cancers, such as breast and lung cancer, without exposure to antibiotics.
Newborn mice lacking YAP1 gene are born without bile ducts. Curiously, they don't die in utero and remain physically active, if small and yellow-tinted.
A University of Houston biomedical researcher is widening the net, looking for symptoms of other proteins -- not just blood - found elevated in colorectal cancer and inflammatory bowel disease. The new biomarkers may one day replace the invasive endoscopy to determine what's going on inside the intestines.
Researchers from Brigham and Women's Hospital have developed a "designer" probiotic -- a thoughtfully engineered yeast that can induce multiple effects for treating IBD.
New research has discovered that common artificial sweeteners can cause previously healthy gut bacteria to become diseased and invade the gut wall, potentially leading to serious health issues. The study, published in the International Journal of Molecular Sciences, is the first to show the pathogenic effects of some of the most widely used artificial sweeteners - saccharin, sucralose, and aspartame - on two types of gut bacteria, E. coli (Escherichia coli) and E. faecalis (Enterococcus faecalis).
For patients who have inflammatory bowel syndrome (IBS), the condition is literally a pain in the gut. Chronic -- or long-term -- abdominal pain is common, and there are currently no effective treatment options for this debilitating symptom. In a new study in ACS Pharmacology & Translational Science, researchers identify a new potential source of relief: a molecule derived from spider venom. In experiments with mice, they found that one dose could stop symptoms associated with IBS pain.
Researchers at Karolinska Institutet in Sweden have analyzed and described in detail the immune cells residing in the human bile duct. The findings may pave the way for new treatment strategies against disorders of the bile duct, which are often linked to immunological processes. The study is published in the journal Science Translational Medicine.
Diet rich in sugar and fat leads to disruption in the gut's microbial culture and contributes to inflammatory skin diseases such as psoriasis. Research shows that switching to a more balanced diet restores the gut's health and suppresses inflammation.